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In the pathogenesis of RA, activated fibroblast-like synoviocytes (FLSs) display proliferative properties similar to those of tumor cells, causing cartilage erosion and ultimately joint destruction

Whether their combination is synergistic, additive, or redundant in humans remains an open research question

A subsequent larger RCT (n=72) confirmed these findings, showing improvements in gait speed, grip strength, exercise capacity, waist circumference, and systolic blood pressure (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

Polygenic prediction of preeclampsia and gestational hypertension

For rate determination, the intensity at 460nm is read periodically and plotted versus time