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& Paulmurugan, R

Careful monitoring of blood glucose levels is crucial, particularly during the initial stages of treatment

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)

It's essential to approach anecdotal evidence with caution, recognizing the individual variability in treatment outcomes

MOTSc: Mitochondriaderived peptide with AMPK activation and insulin sensitivity effects