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Description

Thymoquinone inhibits metastatic phenotype and epithelial-mesenchymal transition in renal cell carcinoma by regulating the LKB1/AMPK signaling pathway

Superoxide activates the AKT signaling pathway, leading to phosphorylation of Mcl-1 at threonine-163 (T163pMcl-1), which stabilizes Mcl-1 and shifts cell survival dependence from BCL-2 to Mcl-1 [127]