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These two isocitrate lyases reversibly catalyze the retro-aldol cleavage of isocitrate and methylcitrate to form glyoxylate and pyruvate, respectively, as well as the same product succinate

The detailed biochemical mechanisms underlying the physiopathology of male infertility are not clearly understood

An increased density implies a higher cell age as has been established by the decreased activities of a number of intracellular enzymes, measured in the lysate (hexokinase, aldolase, pyruvate kinase, glutamate-oxalacetate transaminase) (Table 1)

High intake of sugar-sweetened drinks is strongly linked to MASLD occurrence and progression, with a doseresponse effect seen in long-term studies [113,114,115,116,117,118]