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Other Antioxidant Vitamins Retinoic acid (RA), an active metabolite of retinol (vitamin A), has been shown to have neurotrophic effects and is able to induce upregulation of nerve growth factor (NGF), low-affinity p75 NGF receptors, and high-affinity receptors for neurotrophin-specific tropomyosin-related kinase (trk) [83, 84]

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Mechanical Conditions that Accelerate Intervertebral Disc Degeneration: Overload versus Immobilization

Oxidative stress and inflammation can reinforce one another

But, the specific perks you were seeking, such as skin lightening, detoxification, or better antioxidant support, may fade over time