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have discovered that berberine improves cardioprotection by upregulating miR-340-5p and inhibiting high mobility group box 1 (HMGB1)-mediated inflammatory response (Long et al., 2023)

Firstly, although many drugs show promising results in animal models, there is a lack of sufficient large-scale clinical trial data to support their efficacy and safety across diverse patient populations (206)

Furthermore, TG-C is currently being investigated in ongoing clinical trials for patients with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis (NCT03291470) and symptomatic early hip osteoarthritis (NCT05276011)

Oral zinc intake in an aqueous solution is usually more efficient in terms of absorption than that in a solid-state (Maares and Haase, 2020[283])

The symptoms of insulinoma occur as a result of elevated insulin levels in the blood, usually manifesting as neuroglycopenic and autonomic symptoms [66, 67]