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doi: 10.1186/s12868-015-0161-7 118 RaisonC

There are three subtypes of ionotropic glutamate receptors: The (-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor AMPA The receptor kainate The (N-methyl-D-aspartate) receptor NMDA Each receptor is named for a drug that binds selectively to it

612 Physicochemical properties are an essential component of a drugs pharmacokinetic and pharmacodynamic profile, and they have a significant impact on the success rate of drug candidates during the preclinical development process

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