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If nausea persists, trying pre-bed dosing is an option, though this may slightly reduce efficacy by separating the peptide from morning cortisol elevation

Major insurers might cover these treatments once medical necessity is established with appropriate documentation

Generally, the effects of a skinny shot, such as increased metabolism, improved fat breakdown, and enhanced energy, can last from a few days up to a week after each injection

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Appendices Appendix 1: Literature Search Strategies Literature Search - Vitamin B12 Economic Evidence-Based Analysis Search date: June 3, 2013 Databases searched: OVID MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, EMBASE