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Evidence suggests that well-formulated ascorbic acid preparations may support epidermal turnover and dermal matrix organization, which may help improve barrier resilience in darker skin types prone to reactive conditions

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Other conditions associated with elevated B12 include: Chronic inflammatory states and autoimmune conditions Macro-B12 (B12 bound to immunoglobulins) causing laboratory assay interference without clinical significance Acute inflammatory responses Supplementation and medication should always be considered