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Fecal calprotectin (FCP), a gut-specific inflammatory marker, exhibits superior sensitivity and specificity, more accurately reflecting intestinal inflammation and outperforming CRP in activity monitoring and relapse prediction

Strategies aimed at restoring glutathione homeostasis or reducing oxidative and inflammatory stress could also be explored as possible complements to existing TTR-targeted therapies

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In GBM, the expression of autophagy-related genes such as autophagy-related ( ATG ) 7 , ATG13 , and UNC -51 , such as autophagy-activating kinase 1 (ULK1), is often downregulated, impairing the autophagic capacity of tumors as they progress