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After evidence of clinical improvement, bromocriptine should be decreased by no more than 10% a day since decreasing the dose too rapidly may precipitate a relapse of NMS

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(5) Histone Sumoylation: The addition of small ubiquitin-like modifier ( SUMO ) proteins to histones, typically linked with transcriptional repression

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Otterbein LEBFH, Alam J, Soares M, Tao Lu H, Wysk M, Davis RJ, Flavell RA, Choi AM: Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway