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8.1 Gene modification of MSCs Genetic modification of mesenchymal stem cells (MSCs) using viral or non-viral vectors can induce the overexpression of functional proteins and soluble factors, thereby enhancing stemness, differentiation, migration and homing capabilities, immunomodulation, and other repair-related functions ( in vitro and in vivo ), and improving their resistance to harsh microenvironments and apoptosis

This can cause some discomfort. When you get the vein blood should flow back in to the butterfly tube you can gently pull on the syringe plunger to check this too

Biomed Pharmacother 156:113951 Guo Q, Jin Y, Chen X, Ye X, Shen X, Lin M, Zhang J (2024) NF-B in biology and targeted therapy: new insights and translational implications

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The paper focuses on the peculiar regional case with a specific zoom on the metropolitan area of Turin