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doi: 10.1021/cr60214a002

Given the multifactorial nature of AAs pathogenesis, understanding the role of environmental triggers in the expression of genetic susceptibility is crucial for a more comprehensive understanding of the disease

Nox2 redox signaling maintains essential cell populations in the brain

Adverse Pregnancy Outcomes During pregnancy, high Hcy can cause complications like high blood pressure (e.g., preeclampsia), repeated miscarriages, birth defects, and premature birth

However, while early studies and preclinical findings are promising, robust clinical data directly supporting the efficacy of this specific combination as a standardized therapeutic strategy remains limited