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SSRIs, 5-HT4 partial agonists, 5-HT6 antagonists prevent both cognitive deficits and AD neuropathology and SSRIs increase A clearance in transgenic AD mouse models and humans [126,127,128,129,130,131,132,133,134]

In another study, Tang and co-workers also achieved cervical cancer cell-selective mRNA delivery and CRISPR/Cas9 genome editing by designing phenylboronic acid (PBA) derived LNPs (PBA-BADP/p53 mRNA NPs) to prohibit cancer cell growth and show higher gene expression in HeLa cells over non-cancerous cells (Tang et al., 2019)

Characterizing Bruch's membrane: state-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health

Brain hypermetabolism in amyotrophic lateral sclerosis: a FDG PET study in ALS of spinal and bulbar onset

Increased prevalence of bladder and intestinal dysfunction in amyotrophic lateral sclerosis