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doi: 10.1016/j.immuni.2017.02.013 263 WatanabeD.UchiyamaK.HanaokaK

There are two 2HG enantiomers: D-2-hydroxyglutarate (D2HG) and L-2-hydroxyglutarate (L2HG), with the former predominantly generated from IDH1 mutants and PHGDH while L2HG is primarily generated from the promiscuous activity of LDHA and MDH1/2 under hypoxic or acidic conditions and converted back to 2OG by L2HGDH

TIMER: A web server for comprehensive analysis of tumor-infiltrating immune cells

Oxid Med Cell Longev 2020:9701285

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