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This leads to the accumulation of autophagy receptor proteins like p62 and impairs HDAC6-mediated retrograde transport as well as exocytotic disposal of misfolded proteins

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With the advent of COVID, those numbers are expected to be even higher

Pickering IJ, Prince RC, Salt DE, George GN

The copper ion binding that gives this compound its distinctive blue color and biological activity also makes it sensitive to factors that wouldn't affect simpler peptides