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Supplementary Figure S2 shows that HaCaT cells had an apparent cytotoxic effect with the treatment of 1,600 M of H 2 O 2 , while HFF-1 showed obvious cytotoxicity at 800 M of H 2 O 2 after 2 h incubation

None of these differences in RR reached statistical significance, although the trends were similar to those observed for all-cause dementia

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Aging Biomarker Consortium et al

Importantly, primary human ILC2s exhibited conserved NRF2 activation, glutathione accumulation, and reduced type 2 cytokine production in response to melatonin, underscoring clinical relevance