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Although the total concentration of zinc in the nervous system is remarkably high, healthy neurons contain only trace amounts of free Zn 2+ since its excess is excreted from the cytoplasm by specific Zn 2+ -transporting proteins (ZnTs) into mitochondria, lysosomes or specific vesicles (zincosomes), and/or coordinated by Zn 2+ -buffering proteins (e.g., metallothioneins) 2

Disruption of dopamine homeostasis associated with alteration of proteins in synaptic vesicles: A putative central mechanism of Parkinsons disease pathogenesis

For example, wearing a hat and using sunscreen every day is the best way to stay bright

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The important interaction is: if you have both, you must address methylation support carefully