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Concluding remarks The levels and compartmentalization of NAD + dictate energy state that impinges on normal physiological and biological responses, as indicated by the regulatory role of NAD + in proper redox homeostasis, genomic stability, gene expression, circadian clock, inflammation, metabolism, cellular bioenergetics, mitochondrial homeostasis and adaptive stress responses

This study shows animal declines can disrupt ecological networks in ways that threaten the climate resilience of entire ecosystems that people rely upon, Fricke said