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Conversely, AIF3, lacking these activities, disassembles mitochondrial complexes, increases ROS generation, and simultaneously hinders antioxidant defense

3-Phosphoglycerate is oxidized by phosphoglycerate dehydrogenase (Phgdh) using NAD + to form 3-phosphohydroxypyruvate, which is then converted to phosphoserine in a transamination reaction catalyzed by 3-phosphohydroxypyruvate aminotransferase (Psat)

[18] C677T SNP (Ala 222 Val) The MTHFR nucleotide at position 677 in the gene has two possibilities: C (cytosine) or T (thymine)

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