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Description

Nature 426:895899

Notably, if cysteine or glutathione is present, the dopaquinone reacts with it to ultimately produce the reddish-yellow pheomelanin [86]

Potential therapeutic applications include the use of milk-derived stem cells for tissue engineering and regenerative therapies

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Beyond its cytoplasmic role, ATOX1 can translocate to the nucleus and function as a copper-dependent transcription factor, potentially regulating pathways such as HIF-1 signaling [93] (Figure 4)