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However, the ROS-detoxifying Nrf2 target genes, MnSOD and catalase, were eventually induced but with a significant delayed expression compared with the WT mice

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The study observed a reduction in the Firmicutes/Bacteroidetes ratio in the gut microbiota of individuals with insomnia, alongside an increase in gram-negative and potentially pathogenic bacteria compared to a control group

It improves patients health and quality of life