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Observed effects in human trials Reported adverse events across the IV and oral trials included headache, fatigue, dizziness, nasopharyngitis, diarrhea, flatulence, increased appetite, nausea, and back pain

Nat Med (2017) 23:85968

For instance, dual pH- and redox-responsive polymeric and micellar carriers have been optimized for curcumin, exhibiting controlled degradation and sustained intracellular release in tumor microenvironments (Pillarisetti et al., 2017)

Proline estimation Proline estimation indicated a higher accumulation after the treatments compared to the control, which had a content of 0.140.010 M g -1 FW (Fig