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This weight gain is theorized to be potentially linked to an increase in adipose tissue relative to the overall body mass

And not in a good way

Anti-LINGO-1 antibody treatment alleviates cognitive deficits and promotes maturation of oligodendrocytes in the hippocampus of APP/PS1 mice

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FTH neuron-specific knockout (FTH-KO) mice are more susceptible to ferroptosis after TBI, and the absence of FTH offsets the protective effect of melatonin on ferroptosis induced by TBI, 659 suggesting that melatonin plays a protective role at least in part by inhibiting FTH-mediated ferroptosis in neurons after TBI