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Information sources and search The literature was explored using the MEDLINE (via PubMed) and Web of Science databases, including all articles published from the inception up February 2020

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It is however clear that whilst many non-surgical treatment modalities have emerged, there is still a lack of good quality, randomised data for the majority of these, requiring more investigation to identify the best modality and patient cohort for utilisation

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[8] Biochemistry [edit] Chemical properties [edit] Carnitine is a zwitterion, meaning it has both positive and negative charges in its structure