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Description

CD11b, Integrin alpha M

The histidine residues provide a tertiary structural interaction with the two domains of PrP and copper, that is also protective in function due to involvement of the conserved central region of the protein (Roseman et al., 2020)

Activation of MAPKs in TAO results in the production of pro-inflammatory mediators and activation of fibroblasts, perpetuating inflammation and fibrosis within the orbit (92)