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For in vivo pharmacokinetic analysis, male Sprague-Dawley rats weighing 250 g were cannulated in the right jugular vein

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Anticipating that wild-type mice would exhibit increased susceptibility and a more pronounced response to a higher APAP dose, AAV-transduced wild-type mice were treated with 600 mg/kg APAP for subsequent analysis

Basically, if you can connect the dots and drive the metabolic machinery into the next step, which is stem cell renewal or revival, thats where I think metabolic cardiology is working

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