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10.1182/blood-2011-02-329367 3 AdilM.KandhareA

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In the case of cancer, this process has a dual activity, since it is capable of promoting the survival of cancer cells, through protective autophagy, or participating in the death of these cells, inducing cytotoxic autophagy (116, 117)

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Furthermore, DIM inhibited mouse double minute 2 homolog (MDM2) in colorectal cancer cell lines, inhibiting cell proliferation and inducing cell cycle arrest and apoptosis [123]

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10.1016/j.cca.2010.12.011 44

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Asejeje FO, Akano OP, Ajiboye EO, Adeyemo OA, Ogunro OB (2024) Antioxidant and anti-inflammatory effects of hesperetin in cisplatin-induced male reproductive toxicity in mice

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