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Consistently, antioxidants have been described as exerting double-edged effects, whereby physiological doses may be beneficial, whereas supraphysiological exposure can elicit detrimental cellular responses

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The NMDA receptor structure and function NMDA receptors are typically located on excitatory glutamatergic synapses, although present in many cell types (i.e., GABAergic neurons, dopaminergic neurons, etc.)

Sulfonylurea and/or insulin In a cross-sectional study by Kang et al., it was demonstrated that T2DM patients need to monitor their vitamin B 12 deficiency and keep an ordinary regulation of their vitamin B 12 levels especially those who were prescribed metformin in combination with sulfonylurea