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Description

Sortase mediated protein ubiquitination with defined chain length and topology

The Lancet 324 , 12371239 (1984)

BMC Cancer 13:378 Myzak MC, Dashwood RH (2006) Chemoprotection by sulforaphane: keep one eye beyond Keap1

In addition, CRISPR-engineered reporter systems, such as tyrosine hydroxylase (TH)-linked fluorescent tags and lineage tracers, enable real-time visualization, purification and longitudinal tracking of DA neurons while preserving endogenous regulation, which is crucial for high-content phenotyping and enables the precise assessment of drug effects and screening 43,44,45,46