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The roles of vitamin C in skin health

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demonstrated through comparative experiments that DHI significantly increases lipid peroxidation levels and inhibits GSH, leading to a decrease in the GSH/GSSG ratio and weakened cellular antioxidant capacity, further resulting in the loss of GPX4 activity

In doing so, the glutathione molecule itself becomes a reactive thiyl radical, which quickly pairs with another oxidized glutathione molecule to form glutathione disulfide (GSSG)

Glutathione is one of the most powerful antioxidants in the body as it is the only one that is intracellular