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Malfunctioning of the glutamate/GABAglutamine cycle is a common feature of several brain diseases

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deficiency causes demyelination affecting sensory and motor nerve pathways Common presentations include peripheral neuropathy (glove-and-stocking paraesthesia), unsteadiness, cognitive impairment, and mood changes Neurological symptoms can occur before anaemia develops and may not correlate with serum B12 levels UK treatment for neurological involvement requires hydroxocobalamin 1 mg intramuscularly on alternate days initially, then every two months Treatment should not be delayed whilst awaiting test results when neurological B12 deficiency is suspected, as delays risk permanent damage At-risk groups include older adults, vegans, post-bariatric surgery patients, long-term metformin users, and those exposed to nitrous oxide Table of Contents Not sure where to start

Structure and Function of Glutathione S-Transferases: 9780849345821: Medicine & Health Science Books @ Amazon.com

Neuroprotective: Its ability to reduce neuroinflammation makes it beneficial for brain health