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In our study, FOXO4-DRI was found to effectively promote apoptosis in senescent cells by blocking the FOXO4-P53 interaction and facilitating P53 phosphorylation

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Comparable oxidative stress responses have been observed in other bacteria, including Acinetobacter baumannii and Escherichia coli (7, 50)

mansoni TGR IC 50 Values of TGR Inhibitors with 15-Minute Preincubation Assays The gold complexes AF, aurothioglucose, and aurothiomalate, which are efficient inhibitors (i.e., with low K i /IC 50 values) of mammalian TrxR [29,30], were found also to be efficient TGR inhibitors