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However, ROS may have a cytotoxic effect to cancer cell if the ROS reaches a certain threshold level 56

The alogliptin (20 mg/kg) treatment also exhibited increased expression of the GLP-1 receptor and enhanced the phosphorylation of adenosine monophosphate protein kinase (AMPK) in Wistar Kyoto rats

In: Frost S, McKenna R, editors

Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial