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PMID: 39252968 iScienceHypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE

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doi: 10.1016/j.nicl.2020.102403 [DOI] [PMC free article] [PubMed] [Google Scholar] 146.Hai T, Swansburg R, Kahl CK, Frank H, Stone K, Lemay J-F, et al

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29,30 However, in the periodontitis model, we observed a fundamental reprogramming of GSH metabolism in BM neutrophil, with IFN-I signaling markedly upregulating the degradation-regulatory protein Chac2, which can in turn repressed the catalytic activity of Chac1, 38,39,40,69 resulting in substantial intracellular GSH accumulation