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Unlike other compartments, the ER lacks the reductase needed to convert GSSG back into GSH, making GSSG export vital for maintaining the GSH/GSSG balance

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Judging from historical data, this figure ranks third in the past two decades

Additionally, SF demonstrated protective effects in rodent models of vascular cognitive impairment induced by ischemia at 56.4 mol/kg twice a week (112), subarachnoid hemorrhage at 282 mol/kg every 24 h (113), and intracerebral hemorrhage at 5.64 mol/kg twice a day (114), with upregulation of Nrf2 and reduced inflammation reported in the latter two

Low carbohydrate, high fat diet impairs exercise economy and negates the performance benefit from intensified training in elite race walkers