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Finally, there is the evidence of BPC 157 generation of NO in ex vivo condition (Sikiric et al., 1997a

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J Biol Chem 271:2431324316 Lee M, Schwab C, Yu S, McGeer E, McGeer PL (2009) Astrocytes produce the antiinflammatory and neuroprotective agent, hydrogen sulfide

Finally, the L protein catalyzes the re-oxidation of the lipoyl moiety of the H protein in an NAD + -dependent reaction, generating NADH and a proton (H + )

One possible mechanism is that ROS accumulation due to aberrant oxidative stress in erythroid cells affects erythropoiesis by inducing oxidative denaturation of the band 3 protein