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Prognosis [edit] An elevation in serum bilirubin level of more than 2 times ULN with associated transaminase rise indicates severe hepatotoxicity and is likely to lead to mortality in 10% to 15% of patients, especially if the offending drug is not stopped (Hy's Law)

doi: 10.1016/j.jms.2016.10.020 178 BousisSSetyawatiIDiamantiESlotboomDJHirschAK

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