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Moreover, when comparing the median primaquine exposure in infants to the median primaquine exposure in mothers receiving a single low dose (C MAX = 55.0 ng/mL, AUC = 512 ng h/mL), all of the simulated C MAX and AUC of primaquine in infants were well-below this threshold in the dosing scenarios evaluated

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Marklund et al., 1997) but many mutations affect the binding of zinc while copper remains tightly bound, thus favoring the formation of Zn-deficient SOD

10.1089/hum.2022.147 14 GuH.LiuY.YinD.CaiL.ZhangB.ZhangQ

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