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381 In the CNS, ceruloplasmin is expressed almost exclusively in astrocytes, and its deficiency results in iron overload and formation of iron deposits

Astrocytic processes undergo rapid and reversible morphological remodeling in response to metabolic signals such as fasting and high-fat diet, a process regulated by IKKnuclear factor kappa-light-chain-enhancer of activated B (NF-B) signaling

P., Xu, Y

Of course, it's always best to check in with your GP before starting any dietary supplements, particularly if you have any underlying health conditions or if you're on any medications

The depletion of brain GSH has also been observed from both autopsies as well as in vivo MRS studies with aging and varied neurological disorders (Alzheimers disease, Parkinsons disease, etc.)