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Description

It binds IGFBP-1, IGFBP-2, IGFBP-4, IGFBP-5, and IGFBP-6 with somewhat lower but still substantial affinity

Indeed, the increased locomotor response to amphetamine and other psychostimulants has been used as a simple test to reflect the subcortical hyperdopaminergia underlying the psychotic symptoms in schizophrenia