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In a trial published early this year, 20 healthy middle-aged men consumed cocoa flavanols (twice daily, 450 mg) or control drinks for 1 month, and the results showed that flavanol consumption may mediate the vascular protective effects by modulating the gene expression and DNA methylation and by preserving the integrity of the immunologicalendothelial barrier functions [194]

~ AlphaMD If you're on testosterone replacement therapy , the drinks you're having this weekend might be quietly undermining the very reason you started treatment in the first place

Figure 2 illustrates how NAD decline after DNA damage can lead to mitochondrial dysfunction and how NAD supplementation can be an effective intervention

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