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How to use: Take one capsule daily with food and a full glass of water

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AR45 can act as a negative modulator of AR activity via competitive inhibition of AREs by homodimers or by interfering with coactivator recruitment necessary for AR activity (Jenster et al., 1991

Bartel et al., 2001), (2) the indoleacetamide pathway, which involves the same two P450 enzymes during the initial steps (Pollmann et al., 2002), and (3) the tryptamine (YUCCA) pathway that involves catalysis by tryptophan decarboxylase (TDC) (EC 4.1.1.28) (Takahashi, 1986