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Hospital La Paz Institute for Health Research IdiPAZ (La Paz University Hospital Universidad Autnoma de Madrid), Madrid, Spain, 2 Stroke Code Coordination Center, Servicio de Emergencias Mdicas SUMMA-112, Madrid, Spain, 3 Department of Neurology, Hospital Universitario Clnico San Carlos, Universidad Complutense de Madrid, Madrid, Spain, 4 Department of Neurology and Stroke Center, Hospital Universitario 12 de Octubre, Instituto de Investigacin Hospital 12 de Octubre (i+12), Madrid, Spain, 5 Department of Neurology, University Hospital Puerta de Hierro, Universidad Autonoma de Madrid, Madrid, Spain Background and Aims: In our stroke network, direct transfer to mechanical thrombectomy (MT) center (MT-C) instead of nearest non-MT-capable stroke unit (NSU) is determined by an M-DIRECT score 2

This mechanism is critical as it operates alongside traditional cytotoxic pathways such as granzyme-perforin and Fas-FasL

[DOI] [PubMed] [Google Scholar] 75.Yu S.J

Patients with Graves' disease can exhibit a variety of symptoms related to hyperthyroidism, including diffuse goiter (enlarged thyroid gland), rapid pulse, weight loss and trembling