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Engaging in regular physical activity or exercise training triggers myriad physiological adaptations that offer significant benefits for the prognosis of CVDs either directly or indirectly by modulating redox homeostasis [43,44,45,46,47], including activating antioxidant pathways, mitigating vascular damage and inflammation, and reducing cardiac fibrosis (Fig

doi: 10.1210/en.2017-00600, 79 LaloU.KohW.LeeC