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That is not a reason to dismiss the animal data, but it is a reason to frame it correctly

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4 The most common arthroscopic intervention for chondral injuries is chondroplasty, or removal of the loose pieces of cartilage

Second, promoting FAEE synthesis (by inhibiting the oxidative pathway) worsens symptoms of alcohol-associated acute pancreatitis (132) while inhibiting FAEE synthesis (through pharmacological inhibition of an FAEE synthase) alleviates these symptoms in experimental models, both in vitro and in vivo (133)