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Through a combination of metabolomics and transcriptomics, it was found that malignant breast cancer cell lines (MCF-7 and BCC) exhibit lower activity of the methionine cycle compared to non-malignant cell lines (MCF-10A)

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To rule out that the observed phenotypes are a peculiarity of U-2 OS cells, we verified our results in another cancerous as well as two non-malignant cell lines

[3] Kennedy DO

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