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During pregnancy, placental estrogens drive hepatic adaptations in lipoprotein profiles to supply cholesterol for placental steroid synthesis, mobilize fat and glucose to meet fetal energy demands, and upregulate of P450 enzymes to support waste elimination

Natural antioxidants are bestowed with scavenging and chelation properties and can be alternative for synthetic chelating agents

Wound healing & repair Investigated in animal and cell studies for wound healing and tissue repair via its copper-binding, regenerative activity

Figure 1 Mechanism II Mitochondrial dysfunction causes the release of cytochrome c and induces apoptotic cell death, associated with cell shrinkage, blebbing of plasma membranes, organelle condensation, and fragmentation

Therefore, kidneys, the active members of the hypoxia sensing panel plays an intricate role in regulation of blood pressure, acclimatization and development of high altitude maladies