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NAC regulates lysosomal degradation of Notch2 To further explore the mechanism underlying NAC-mediated down-regulation of Notch2, the mRNA level of Notch2 was detected

Edwards also predicted, based on our prior research there would be higher levels of Legionella, due to the lack of corrosion control

We conducted the first-in-human trial of gene editing therapy in MMA, which enrolled young pediatric participants

Given the association between hypoxia and MS pathogenesis, it is tempting to speculate that regulating HIF-1 may be possible to improve the local hypoxic microenvironment in MS patients, reducing vascular inflammation and fibrosis, and ultimately alleviating clinical symptoms

In these districts GSH is predominantly in the reduced form except for endoplasmic reticulum where the oxidized form is mainly present being necessary for the correct folding and secretory pathway of proteins (Hwang et al., 1992)