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To elucidate these regulation circuits and to investigate whether mTOR signaling might be involved in this abnormality, we performed gene set enrichment analysis (GSEA) on differentially expressed genes of Gclc -sufficient MZB vs

A study (Tedeschi and Secondo, 2022) identified transient receptor potential channel mucolipin-1 (TRPML1) as a sensor of intracellular ROS in neurons

We explore the glucose divergence into the PPP and OXPHOS as well as the creation of ROS through mitochondrial leakage and the mitigation of ROS by the GSH redox system